GreenMark News/Events


Technology Insights: LumiCare caries detection rinse from GreenMark BioMedical

October 21, 2020 – GreenMark BioMedical founder and CEO Steven Bloembergen, Ph.D. explains the new LumiCare caries detection rinse which was named a 2020 Cellerant Best of Class Technology award winner.

Watch the video at Dental Products Report


GreenMark Recognized as a 2020 Best of Class Technology Award Winner

September 2, 2020 – GreenMark Biomedical Inc. announced that the company has been selected as a 2020 Cellerant Best of Class Technology Award recipient.

“Announcing the award winners is especially meaningful this year,” said Dr. Lou Shuman, DMD, CAGS, CEO of Cellerant and founder of the Best of Class Technology Awards. “The Chicago Midwinter, where the Best of Class Panel selected the award winners, was really the last in person event for the dental community in 2020. Dentists and their staff, as well as dental products and technology vendors have overcome many unbelievable challenges since that time. It’s exciting and uplifting to change the narrative for a moment by recognizing these deserving award winners and sharing these amazing technologies with our colleagues.”

Read the press release. | View the award presentation.


GreenMark Biomedical Secures Follow-On Investment

August 24, 2020 – GreenMark Biomedical Inc. announced that the company raised $1.74M in equity financing in the form of convertible notes in anticipation of a Series A financing in 2021.

Read the press release.


Changing The Way We See Caries – Literally

May 11, 2020 – Typically the purview of science fiction writers and medical researchers, nanotechnology isn’t something dental professionals are asked to think about very often, let alone incorporate into their daily clinical practice. As more people learn about what GreenMark Biomedical makes possible, that will certainly change.

Read the article at Oral Health.


GreenMark Secures Follow-On Funding for Regenerative Treatment Technology

May 20, 2020 – GreenMark Biomedical Inc. along with its collaborators at the University of Michigan (U-M) today announced that its technology on regenerative treatment of tooth enamel has received support at up to $913,000 from the Michigan-Pittsburgh-Wyss Regenerative Medicine (MPWRM) Resource Center (NIH grant number: U24-DE029462).

Read the press release.


Focus On: Disruptive Technologies for 2020

March 27, 2020 – Lou Shuman, DMD, CAGS, discusses some new technologies that can make a significant impact in your practice.

I love what I do. Introducing companies to the dental market and helping accelerate the impact of existing ones, I get a front row seat to the innovations that are reshaping critical aspects of our industry, from clinical care to practice management. As founder of the Cellerant Best of Class Technology Awards, I have the privilege of hearing what our panel of technology experts—including Dr. Paul Feuerstein, technology editor of Dentistry Today—consider cutting-edge. I’ve selected 4 from the many innovations to share with you, because I believe they stand to make a significant impact in your practice this year.

Read the article at Dentistry Today.


Dental Product Presentation: LumiCare from GreenMark Biomedical

March 12, 2020 – GreenMark Biomedical Founder and CEO Steven Bloembergen, PhD explains the novel caries detection technology his company created and how it can be used to easily identify dental caries using a curing light likely already in the dental practice.

Watch the video at Dental Products Report


Highlights from the 2020 Chicago Midwinter Meeting

March 9, 2020 – From pink curing lights, to tooth jewelry, to late-night deliberations…it was a great year for Chicago Midwinter.

The 2020 Chicago Midwinter Meeting was held late last month—and it did not disappoint! Whoever says that dental conferences are dying is certainly not talking about this meeting. There was a crowd in the exhibit hall every day and the educational courses were fantastic.

Read the article at DentistryIQ


GreenMark Makes Its Debut at the Chicago Dental Society Midwinter Meeting

February 20-22, 2020 – GreenMark exhibited at the Chicago Dental Society Midwinter Meeting at the McCormick Center, Feb. 20-22, 2020. What follows is a brief introduction and then a pictorial summary of the first major exhibit and “soft launch” event for the team introducing GreenMark’s technology platform and first product LumiCare™ Caries Diagnostic Rinse, to become available in 2020, pending 510(k) Clearance by FDA.

Read the event summary.


Can You Imagine This?

Dental Economics, December 9, 2019 – In 1971, John Lennon famously asked us to imagine a different world. His words still resonate today, and we can apply them to our own dental world.

Can you imagine people living without secondary caries? Can you imagine if we could treat white spots noninvasively? We don’t have to imagine anymore. Let me introduce to you incredible upcoming technologies from Nobio and GreenMark Bio.

Read the full article (PDF). | Read the article at Dental Economics.


GreenMark Secures Phase II SBIR Funding for Identification of Early Stage Dental Caries

East Lansing and Ann Arbor, MI – October 2, 2019 – GreenMark Biomedical Inc. today announced it has been awarded a $1.5m Phase II Small Business Innovation Research (SBIR) grant to further develop its patented nanoparticle-based dental technology for detection of early stage dental caries. The 2-year project involves collaboration with dental and biomaterials experts at the University of Michigan, Creighton University, Tufts University and University of Colorado, and is being funded by the National Institute of Dental and Craniofacial Research (NIDCR) of the National Institutes of Health (NIH).

Read the press release. | Newswire

Early stage caries detection


After the Elevator Pitch

Fall 2019 – GreenMark Biomedical Inc. is a Michigan-based, minimally invasive healthcare company that was founded in 2016 by Dr. Steven Bloembergen with a mission to “enable dentists to preserve teeth through early diagnosis and treatment”. Dr. Bloembergen is a co-founder of EcoSynthetix Inc., a global bio-based nanoparticle manufacturer. In partnership with collaborators at the University of Michigan, GreenMark has expanded upon this proprietary technology by applying it to medicine and dentistry.

Read the full article.


Bringing Early-Stage Carious Lesions to Light

September 30, 2019 – Using nanotechnology, GreenMark Biomedical is developing a non-invasive approach to diagnosing and treating active, incipient carious lesions.

The idea of nanodentistry may still seem a little like pure science fiction or a distant vision. In fact, products based on “small scale” targeted technology for diagnosing, treating and preventing caries may well be in your practice in the near future.

Read the full article at Dental Products Report.


GreenMark Secures Additional Funding for Cavity Identification and Treatment

East Lansing and Ann Arbor, MI – March 19, 2019 – GreenMark Biomedical Inc. today announced it secured $670K equity funding completing a $1.2M Series Seed Preferred Stock round to further develop and commercialize its patented nanoparticle-based dental technology. The University of Michigan’s MINTS program, Invest Michigan and Red Cedar Ventures investments follow earlier funding from Blue Water Angels, Western Michigan University’s BRCC and Invest Detroit Ventures.

Read the press release. | Newswire


GreenMark Wins $100,000 in Funding at Accelerate Michigan: Reasons to be Thankful at Thanksgiving!

Detroit, MI – Nov. 21, 2018 – GreenMark Biomedical Inc. today announced it was awarded the $100,000 Second Prize at the 2018 Accelerate Michigan Innovation Competition (AMIC), which includes an investment from Invest Michigan and ID Ventures as well as a $25,000 grant. AMIC supports Michigan’s entrepreneurial ecosystem by inviting entrepreneurs to showcase their companies to Angel and Venture Capital investors, while building connections with fellow entrepreneurs and business acceleration resources.

Read the press release. | Newswire


GreenMark Secures Funding for Cavity Identification and Treatment Technology

Ann Arbor, MI – October 3, 2018 – GreenMark Biomedical Inc. today announced it secured funding for its patented dental technology that identifies ‘pre-cavities’ which can be treated non-invasively before becoming cavities. This will have major implications for treatment of tooth decay prior to the need for surgical treatment, resulting in improved oral health outcomes for patients.

Read the press release. | Newswire


GreenMark Biomedical Raises Seed Investment

Ann Arbor, MI – June 29, 2018 – GreenMark Biomedical Inc. today announced that it closed on $500K in equity investment. The round is led by BlueWater Angel Investment Network (BWA) of Saginaw, MI and funds flowed in May and June as part of a Rolling Close. Biosciences Research & Commercialization Center (BRCC), an early stage Life Science Investor out of Kalamazoo, MI also participated.

Read the press release.


GreenMark to Present at the 37th Annual Michigan Growth Capital Symposium and Coulter Investment Forum May 15-16

Ann Arbor, MI – May 14, 2018 – GreenMark Biomedical Inc. today announced that it has been selected to present at the 37th annual Michigan Growth Capital Symposium (MGCS). GreenMark, a Delaware corporation with facilities in Michigan will be presenting to investors in attendance, including more than 100 top venture capital firms.

Read the press release.


GreenMark Biomedical and University of Michigan Receive Phase I SBIR Funding for Diagnostic to Enable Minimally Invasive Dentistry

April 4, 2018 – GreenMark Biomedical Inc. today announced that it has received a Phase I Small Business Innovation Research (SBIR) grant in the amount of US $228,883 from the National Institutes of Health (NIH). The grant will fund a collaborative project between GreenMark and the University of Michigan (U-M).

Read the press release.


GreenMark Announced as Semifinalist for the 8th Annual Accelerate Michigan Innovation Competition

October 3, 2017 – The stage is set for the 8th Annual Accelerate Michigan Innovation Competition, the state’s largest convening of high-growth, high-tech companies and venture investors. Today, 36 innovative startups from a variety of high-growth sectors including advanced materials, manufacturing, alternative energy, business services, consumer products, information technology, life sciences/healthcare, media, mobility and more, learned they are this year’s semifinalists.

Read the press release.


GreenMark Publication Highlighted in Advanced Science News

Our peer-reviewed publication, entitled “Nanoparticle-based targeting and detection of microcavities” published in Advanced Healthcare Materials is being highlighted in Advanced Science News.

Read the article.


GreenMark Selected to Participate in VentureWell ASPIRE Program

June 5, 2017 – GreenMark has been selected to partner with VentureWell through the ASPIRE Healthcare program.  ASPIRE is an intense experiential workshop that prepares startups for the investments and partnerships necessary to launch their ventures.  The program will be held at Detroit’s Techtown, June 26-June 30, 2017.  Participants will engage with fellow healthcare startups and work with mentors who are experts in early-stage financing from around the country.

See the June 2017 cohort | Learn more about ASPIRE


GreenMark to Present at the 36th Annual Michigan Growth Capital Symposium and Coulter Investment Forum May 16-17

Ann Arbor, MI – May 9, 2017 – GreenMark Biomedical Inc. today announced that it has been selected to present at the 36th annual Michigan Growth Capital Symposium (MGCS) and the jointly hosted Coulter Investment Forum. GreenMark, a Delaware corporation with facilities in Michigan will be presenting to investors in attendance, including more than 100 top venture capital firms. The company aims to deliver health benefits to society through biobased targeting technologies.

Read the full article (PDF).


Brad Martin, MTRAC Life Science Program Director, awards Wendy Bloembergen, Nathan Jones and Steven Bloembergen the Overall Winner Award

Biomedical Commercialization Course Awards Winning Team

Ann Arbor, MI – Nov 17, 2016 – On Friday, November 4, Fast Forward Medical Innovation ended the fifth cohort of the Early Tech Development (ETD) Course with a competition in which teams pitched their projects to the class and a panel of judges.  Thirteen project teams graduated from the 4-week program that is designed to provide the knowledge and tools needed to navigate the initial process of innovation and commercialization.  Congratulations to the winning project teams!

Overall Winner & Therapeutics/Diagnostic Track Winner:
Wendy Bloembergen, Steven Bloembergen, and Nathan Jones for the presentation of a starch nanoparticle for detection of early-stage cavities

Read the full article


GreenMark-AHM-coverNanoparticle-Based Targeting and Detection of Microcavities

Advanced Healthcare Materials, January 11, 2017 – Although dental caries is the most prevalent oral disease worldwide, currently, many dentists continue to use the traditional mirror and probe (dental explorer) method of caries diagnosis. This method of caries detection has the drawback that it is often difficult to distinguish between active and inactive carious lesions. In this work, novel bio-based nanoparticles are developed to specifically detect active caries in vitro. The nanoparticles are made from a cationic fluorescein-labeled food-grade starch in order to fluoresce when illuminated by a standard dental curing light, and to degrade in the oral cavity into nontoxic compounds after detecting the active carious lesion. When exposed to extracted human teeth, cationic fluorescent (+5.8 ± 1.2 mV) nanoparticles (size 101 ± 56 nm) selectively illuminate active caries, but not the healthy tooth surface. Two-photon microscopy confirms the selective binding and accumulation of cationic fluorescent nanoparticles into microscopic carious pores in enamel. These novel nanoparticles provide a unique method to assist in the early diagnosis of active carious lesions with the potential to directly impact dental treatment.

Read the full article (PDF)


Nathan Jones Wins 2016 IADR Colgate Research in Prevention Travel Award

Nathan Jones, previously at the University of Waterloo and currently at the University of Michigan, won the 2016 IADR Colgate Research in Prevention Travel Award. The objective of this award program is to encourage young investigators to undertake research in the prevention of oral diseases and to facilitate their presentation of this work to the international dental and oral health research community.

Learn More about the award


GreenMark Biomedical Introductory Press Release

Lansing, MI – June 10, 2016 – GreenMark Biomedical Inc. today announced an agreement relating to the transfer of certain intellectual property from EcoSynthetix Inc. (TSX: ECO), a renewable chemicals company that produces a portfolio of biobased products. GreenMark, a Delaware start-up corporation with facilities in Michigan, was formed for the purpose of delivering health benefits to society through biobased targeting technologies. The company will be developing and commercializing a platform of diagnostic and therapeutic technologies using biobased, nano-scale targeting particles.

Read the full press release


GreenMark has a collaboration network with US and Canadian universities involving health based technologies.  Nathan Jones, previously at the University of Waterloo and currently at the University of Michigan, has been working with the biopolymer nanoparticles since 2009.  He will be presenting some of the findings of his Ph.D. research at the International Association for Dental Research (IADR) 94th General Session & Exhibition, in Seoul, Korea.

2016-IADR-award-letter2016 IADR Cariology Research Group Science Award

View PDF


Did you know that the American Dental Association (ADA) reported approximately 200 million Americans did not see a dentist in the past year?

Read the information from the American Dental Association (PDF)